Rsk-1(Phospho Ser380) Polyclonal Antibody, 50ul Mammalian Expression PDGFRB is flanked on chromosome

PDGFRB is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor

and a cytoplasmic region

The protein encoded by this gene belongs to the phosphatase 2A regulatory subunit B family

The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex

Rsk-1(Phospho Ser380) Polyclonal Antibody, 50ul Mammalian Expression PDGFRB is flanked on chromosomeThis gene encodes a member of the RSK (ribosomal S6 kinase) family of serine threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates including members of the mitogen activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants encoding different isoforms have been