GRP3 Polyclonal Antibody, 100ul Deep Well Plates Also detected in hepatoblastoma HepG2

Also detected in hepatoblastoma HepG2 cells

the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63

Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins

Defects in this gene are a cause of macular corneal dystrophy (MCD)

GRP3 Polyclonal Antibody, 100ul Deep Well Plates Also detected in hepatoblastoma HepG2Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP GDP regulated switches that cycle between inactive GDP and active GTP bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000