DNA Ligase III Polyclonal Antibody, 100ul Roller Bottles All GTPases of the Ras

All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding

Mutations in this gene cause glycogen storage disease type 9A| also known as X-linked liver glycogenosis

autoimmune disease

Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function

DNA Ligase III Polyclonal Antibody, 100ul Roller Bottles All GTPases of the RasLIG3 is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. DNA ligase 3 encoded by LIG3 is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon