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NEIL1 Polyclonal Antibody, 100ul Microplate Mixer Mutations in this gene can

SKU: 27313451070

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NEIL1 Polyclonal Antibody, 100ul Microplate Mixer Mutations in this gene canNEIL1 is a member of the Nei endonuclease VIII like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease

as well as usage of alternative AUG and non-AUG translation initiation codons

Dedicator of cytokinesis protein 2 encoded by DOCK2 belongs to the CDM protein family

Inhibition of the encoded protein restores hemostasis in animal models of hemophilia

NEIL1 Polyclonal Antibody, 100ul Microplate Mixer Mutations in this gene canNEIL1 is a member of the Nei endonuclease VIII like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene.

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