Topo I Polyclonal Antibody, 20ul Culture Media Atrophin-1 contains a polyglutamine repeat

Atrophin-1 contains a polyglutamine repeat

These proteins also share structural homology with TNF family members

blocking actin-myosin interactions and thereby mediating striated muscle relaxation

The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation

Topo I Polyclonal Antibody, 20ul Culture Media Atrophin-1 contains a polyglutamine repeatTOP1 (topoisomerase (DNA) I) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. TOP1 is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.