DPM3 Rabbit Polyclonal Antibody, 100ul 3D Cell Culture Consumables This gene is located in

This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer

Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis

and its gene mutation and increased expression may be associated with human cancer

It may be a component of a prelamin A endoprotease complex

DPM3 Rabbit Polyclonal Antibody, 100ul 3D Cell Culture Consumables This gene is located inDolichol phosphate mannose (Dol P Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol P Man results in defective surface expression of GPI anchored proteins. Dol P Man is synthesized from GDP mannose and dolichol phosphate on the cytosolic side of the ER by the enzyme dolichyl phosphate mannosyltransferase. The protein encoded by this gene is a subunit of dolichyl phosphate mannosyltransferase