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Huntingtin(Phospho Ser421) Polyclonal Antibody, 50ul Proteases and competes with E1A for

SKU: 28057814277

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Huntingtin(Phospho Ser421) Polyclonal Antibody, 50ul Proteases and competes with E1A forHuntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product. A fairly broad range of trinucleotide repeats (9 35) has been identified in normal controls, and repeat numbers in excess of 40 have been described as

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Description

and competes with E1A for binding sites in p300/CBP

As a scaffold protein involved in cell polarization processes| this protein binds to many other proteins

Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II)

retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment

Huntingtin(Phospho Ser421) Polyclonal Antibody, 50ul Proteases and competes with E1A forHuntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product. A fairly broad range of trinucleotide repeats (9 35) has been identified in normal controls, and repeat numbers in excess of 40 have been described as

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