AIRE-1 Polyclonal Antibody, 50ul[BT-AP00312] DNA Oligo Synthesis This gene is the putative

This gene is the putative transforming gene of avian sarcoma virus 17

The encoded protein may function as a transcription factor

functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass

and a cytoplasmic domain with predicted serine/threonine specificity

AIRE-1 Polyclonal Antibody, 50ul[BT-AP00312] DNA Oligo Synthesis This gene is the putativeAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein (autoimmune regulator) plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with