GPS2 Polyclonal Antibody, 100ul Centrifugal Filter Expression is slightly down-regulated by

Expression is slightly down-regulated by dexamethasone and slightly up-regulated by IL-10

This gene product

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and these opposite actions are thought to be mediated by two classes of receptors

GPS2 Polyclonal Antibody, 100ul Centrifugal Filter Expression is slightly down-regulated byGPS2 encodes G protein pathway suppressor 2 involved in G protein mitogen activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS and MAPK mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1 HDAC3 (nuclear receptor corepressor 1 histone deacetylase 3)