MYOZ2 Polyclonal Antibody, 100ul Cytokines Alternative splicing results in multiple

Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 1

TBX2 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain

Multiple transcript variants encoding distinct isoforms have been identified for RGS12

which is thought to be an exon splice enhancer

MYOZ2 Polyclonal Antibody, 100ul Cytokines Alternative splicing results in multipleThe protein encoded by MYOZ2 (myozenin 2) belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha actinin at the z line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in MYOZ2 cause cardiomyopathy familial hypertrophic type 16, a