Sclerostin Polyclonal Antibody, 20ul Liquid Storage Consumables Both calcium/calmodulin and protein phosphorylation

Both calcium/calmodulin and protein phosphorylation mechanisms control its activity

It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs)

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and it may also mediate both cell proliferation and cell death

Sclerostin Polyclonal Antibody, 20ul Liquid Storage Consumables Both calcium/calmodulin and protein phosphorylationSclerostin (SOST) is a secreted glycoprotein with a C terminal cysteine knot like (CTCK) domain and sequence similarity to the DAN (differential screening selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss of function mutations in SOST are associated with an autosomal recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of SOST, which causes reduced