Histone H2A.Z (Acetyl Lys12) Rabbit Polyclonal Antibody, 20ul Bacterial Expression This nuclear gene encodes polypeptide

This nuclear gene encodes polypeptide 1 (muscle isoform) of subunit VIIa and the polypeptide 1 is present only in muscle tissues

Interacts with RRN3/TIF-IA

and has a role in apoptosis and cancer

it may regulate DNA replication by chromatin acetylation and act as a coactivator of TP53-dependent transcription

Histone H2A.Z (Acetyl Lys12) Rabbit Polyclonal Antibody, 20ul Bacterial Expression This nuclear gene encodes polypeptideVariant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation DNA repair DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones also called histone