DR4 Polyclonal Antibody, 100ul Lysosome cAMP responsive element binding protein

cAMP responsive element binding protein 1 binds as a homodimer to the cAMP-responsive element

In addition| this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity

Defects in this gene can also cause cone-rod dystrophy type 11| a disease characterized by the initial degeneration of cone photoreceptor cells and resulting in loss of color vision and visual acuity| followed by the degeneration of rod photoreceptor cells| which progresses to night blindness and the loss of peripheral vision

It is uncertain whether Met-1 or Met-50 is the initiator

DR4 Polyclonal Antibody, 100ul Lysosome cAMP responsive element binding proteinTNF receptor superfamily member 10a encoded by TNFRSF10A is a member of the TNF receptor superfamily. This receptor is activated by tumor necrosis factor related apoptosis inducing ligand (TNFSF10 TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.