PIAS 1 Polyclonal Antibody, 100ul Enzyme Activity Assays an autosomal recessive disease associated

an autosomal recessive disease associated with a susceptibility to pyogenic infections

Able to catalyze nucleosome sliding in an ATP-dependent manner

It can also induce proliferation in peripheral monocytes

It can have an affect on one step in the endoplasmic to Golgi trafficking

PIAS 1 Polyclonal Antibody, 100ul Enzyme Activity Assays an autosomal recessive disease associatedPIAS1 encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Protein inhibitor of activated STAT 1 plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript