p53(Phospho Thr18) Polyclonal Antibody, 100ul Cell Function Analysis non-erythrocytic 1) is one member

non-erythrocytic 1) is one member of a family of beta-spectrin genes

This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade

Most members of family 1 have two conserved glutamic acid residues| which are required for enzymatic activity

it is mainly confined to duodenal and stomach endoderm

p53(Phospho Thr18) Polyclonal Antibody, 100ul Cell Function Analysis non-erythrocytic 1) is one memberThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.