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Ku-70 (Acetyl Lys539) Polyclonal Antibody, 20ul CellSafe™ nuclear DNA-binding protein regulates transcription

SKU: 2999764662

4.3
SEK97.20 SEK122.20

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Ku-70 (Acetyl Lys539) Polyclonal Antibody, 20ul CellSafe™ nuclear DNA-binding protein regulates transcriptionThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

nuclear DNA-binding protein regulates transcription

GO annotations related to this gene include hydrolase activity

displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID: 15866175)

An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin

Ku-70 (Acetyl Lys539) Polyclonal Antibody, 20ul CellSafe™ nuclear DNA-binding protein regulates transcriptionThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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