TRAP230 Polyclonal Antibody, 20ul Organelle Studies MLLT10 encodes a transcription factor

MLLT10 encodes a transcription factor (myeloid/lymphoid or mixed-lineage leukemia

The protein is necessary for STK11-induced G1 cell cycle arrest

Growth associated protein 43 encoded by GAP43 has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration

potent neurotrophic factors that play key roles in the control of neuron survival and differentiation

TRAP230 Polyclonal Antibody, 20ul Organelle Studies MLLT10 encodes a transcription factorThe initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1. MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by the gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C. The CDK8 subcomplex modulates Mediator polymerase II interactions