NFKappaB-p105 Polyclonal Antibody, 50ul[BT-AP05977] Adenovirus Packaging Two chains of the factor

Two chains of the factor are held together by 1 or more disulfide bonds

GO annotations related to this gene include protein homodimerization activity and protein kinase activity

It also interacts with multiple proteins including calmodulin| CABP1| enkurin| Na(+)-H+ exchange regulatory factor (NHERF )| interferon-induced GTP-binding protein (MX1)| ring finger protein 24 (RNF24)| and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1)

and adhesion (summary by Eiseler et al

NFKappaB-p105 Polyclonal Antibody, 50ul[BT-AP05977] Adenovirus Packaging Two chains of the factorNFKB1 encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF kappa B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra and extra cellular stimuli such as cytokines, oxidant free radicals, ultraviolet irradiation, and