MED31 Polyclonal Antibody, 20ul Gel & Buffers Mutations in this gene have

Mutations in this gene have been linked to cryptogenic cirrhosis

This gene is expressed in cardiac and skeletal muscle and may play an important role in these tissues during development

MLH1 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC)

JUN is intronless and is mapped to 1p32-p31

MED31 Polyclonal Antibody, 20ul Gel & Buffers Mutations in this gene haveComponent of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II dependent genes. Mediator functions as a bridge to convey information from gene specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with