Bcl-2 Polyclonal Antibody, 50ul[BT-AP00859] Microbial Genome Editing RAD17 checkpoint clamp loader component

RAD17 checkpoint clamp loader component binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage

An important paralog of this gene is ABHD12

a complex required to maintain the transcriptionally repressive state of many genes

Netrin is included in a family of laminin-related secreted proteins

Bcl-2 Polyclonal Antibody, 50ul[BT-AP00859] Microbial Genome Editing RAD17 checkpoint clamp loader componentBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.