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HRI Polyclonal Antibody, 100ul Peripheral Blood Separation Tube This gene and the gene

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HRI Polyclonal Antibody, 100ul Peripheral Blood Separation Tube This gene and the geneEukaryotic translation initiation factor 2 alpha kinase 1encoded by EIF2AK1 acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.

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Description

This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y

An important paralog of this gene is SLC38A1

The activity of this receptor is mediated by G proteins which activate adenylyl cyclase

and proteolytic processing significantly affect the activity of this protein

HRI Polyclonal Antibody, 100ul Peripheral Blood Separation Tube This gene and the geneEukaryotic translation initiation factor 2 alpha kinase 1encoded by EIF2AK1 acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.

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