LIMK-1/2(Phospho Thr508/505) Polyclonal Antibody, 100ul Cryopreservation Tumor protein p53 responds to

Tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes

Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2

which contain a PTP domain and a characteristic C-terminal prenylation motif

purity levels

LIMK-1/2(Phospho Thr508/505) Polyclonal Antibody, 100ul Cryopreservation Tumor protein p53 responds toThere are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N terminal LIM motifs and a C terminal protein kinase