Microcephalin Polyclonal Antibody, 50ul Pathway and Network Analysis Members of the WIPI subfamily

Members of the WIPI subfamily of WD40 repeat proteins| such as WIPI2| have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al

Mouse studies suggest that this gene functions during normal adipose tissue development and may play a role in human triglyceride metabolism

prostaglandin-endoperoxide synthase 1 has been identified as a moonlighting protein

Unlike most mitochondrial matrix proteins

Microcephalin Polyclonal Antibody, 50ul Pathway and Network Analysis Members of the WIPI subfamilyThis gene encodes a DNA damage response protein. The encoded protein may play a role in G2 M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.