Dvl-2 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation This gene encodes a secreted

This gene encodes a secreted chemotactic protein that initiates chemotaxis via the ChemR23 G protein-coupled seven-transmembrane domain ligand

Alternatively spliced transcript variants encoding distinct isoforms have been reported

A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development

The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds

Dvl-2 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation This gene encodes a secretedDVL2 encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. DVL2 encodes a 90 kD protein that undergoes posttranslational phosphorylation to form a 95 kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved