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MAGA4 Polyclonal Antibody, 20ul Cell Culture pre-angiotensinogen or angiotensinogen precursor

SKU: 33364713057

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MAGA4 Polyclonal Antibody, 20ul Cell Culture pre-angiotensinogen or angiotensinogen precursorThis gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some

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Description

pre-angiotensinogen or angiotensinogen precursor

The product of this gene binds to chemokine receptors CCR3 and CCR10

Overexpression of this gene may play a role in leukemogenesis| and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein

This protein may also play a role in maintaining the membrane permeability barrier| and knockdown of this gene in human cells results in the release of cytochrome c and apoptosis

MAGA4 Polyclonal Antibody, 20ul Cell Culture pre-angiotensinogen or angiotensinogen precursorThis gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some

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