MDC1(Phospho Ser513) Polyclonal Antibody, 100ul Cell Culture the product of myeloproliferative leukemia

the product of myeloproliferative leukemia virus oncogene

This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions

The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites| implicating a role in determining and stabilizing dentritic shape during neuron development

Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals

MDC1(Phospho Ser513) Polyclonal Antibody, 100ul Cell Culture the product of myeloproliferative leukemiaThe protein encoded by this gene contains an N terminal forkhead domain, two BRCA1 C terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41 amino acid sequence. The encoded protein is required to activate the intra S phase and G2 M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double strand breaks through its BRCT motifs, and