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HoxB4 Polyclonal Antibody, 100ul NGS Oligos 53BP1 activates the checkpoint kinase

SKU: 35145529463

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HoxB4 Polyclonal Antibody, 100ul NGS Oligos 53BP1 activates the checkpoint kinaseHOXB4 is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. Homeobox protein Hox B4 functions as a sequence specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for

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Description

53BP1 activates the checkpoint kinase ATM and promotes DNA double strand break repair via nonhomologous end joining (NHEJ) repair pathway

and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42

After microtubule disassembly| TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al

Recognizes and binds to the DNA sequence 5'-

HoxB4 Polyclonal Antibody, 100ul NGS Oligos 53BP1 activates the checkpoint kinaseHOXB4 is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. Homeobox protein Hox B4 functions as a sequence specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for

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