Glypican-5 Polyclonal Antibody, 50ul Immunoassays Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been described for GFRA4

A translocation involving the MLL gene and SEPT5 has also been reported in patients with acute myeloid leukemia

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Mutations in this gene are the cause of Wagner syndrome type 1

Glypican-5 Polyclonal Antibody, 50ul Immunoassays Alternatively spliced transcript variants encodingCell surface heparan sulfate proteoglycans are composed of a membrane associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.