IGF-IR Polyclonal Antibody, 20ul[BT-AP04397] Recombinant Protein Expression Mutations in this gene result

Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions

Two transcript variants encoding different isoforms have been found for NOTCH2

has been found in cases of myeloproliferative disorder

ETS transcription factor) belongs to the ETS transcription factor family

IGF-IR Polyclonal Antibody, 20ul[BT-AP04397] Recombinant Protein Expression Mutations in this gene resultIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms