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HAP1 Polyclonal Antibody, 20ul Thermo Mix in addition to its metabolic

SKU: 35346940670

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HAP1 Polyclonal Antibody, 20ul Thermo Mix in addition to its metabolicHuntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase

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Description

in addition to its metabolic functions

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins

The encoded protein may play an important role in embryogenesis| particularly in neuronal cells| as well as in lymphocyte development and survival

The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends

HAP1 Polyclonal Antibody, 20ul Thermo Mix in addition to its metabolicHuntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase

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