RUFY1 Polyclonal Antibody, 100ul Cell Culture Flasks is a 648 amino acid

is a 648 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one protein kinase domain

This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport

PIAS4 also alters the nuclear localization

enzyme regulation:Activated by phosphorylation on Thr-174 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39

RUFY1 Polyclonal Antibody, 100ul Cell Culture Flasks is a 648 amino acidRUFY1 (RUN and FYVE domain containing 1) encodes a protein that contains a RUN domain and a FYVE type zinc finger domain. The encoded protein binds to phosphatidylinositol 3 phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for RUFY1.