Rock-1 Polyclonal Antibody, 50ul[BT-AP13880] Purification Defects in this gene are

Defects in this gene are a cause of polycystic kidney disease (PKD)

which catalyzes the removal of the 3' trailer from precursor tRNAs

Mutations in this gene have been associated with autosomal recessive mental retardation

A transcribed pseudogene of this gene has been identified on chromosome 15

Rock-1 Polyclonal Antibody, 50ul[BT-AP13880] Purification Defects in this gene areThis gene encodes a protein serine threonine kinase that is activated when bound to the GTP bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP bound form and the active GTP bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response