DOC2B Rabbit Polyclonal Antibody, 50ul Gel & Buffers Mutations in this gene cause

Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma

It is not expressed in normal tissues

RIMKLA contains one ATP-grasp domain and binds two manganese ions per subunit

Several transcript variants encoding different isoforms have been found for CCND3

DOC2B Rabbit Polyclonal Antibody, 50ul Gel & Buffers Mutations in this gene causeThere are at least two protein isoforms of the Double C2 protein namely alpha (DOC2A) and beta (DOC2B) which contain two C2 like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC 2. DOC2B is expressed ubiquitously and is suggested to be involved in Ca(2+) dependent intracellular vesicle trafficking in various types of cells.