PLC gamma2(Phospho Tyr753) Polyclonal Antibody, 50ul Bacterial Expression Calpains constitute a family of

Calpains constitute a family of intracellular calcium-dependent cysteine proteases

Mutations in TUBA1A cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly

prolonging the half-life of IGFs and altering their interaction with cell surface receptors

extracellular collagenous domain

PLC gamma2(Phospho Tyr753) Polyclonal Antibody, 50ul Bacterial Expression Calpains constitute a family ofThe protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1 phosphatidyl 1D myo inositol 4,5 bisphosphate to 1D myo inositol 1,4,5 trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in