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Paxillin(Phospho Tyr118) Polyclonal Antibody, 20ul Measuring Instruments inhibiting oncogenic beta-catenin-mediated transcriptional activation

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Paxillin(Phospho Tyr118) Polyclonal Antibody, 20ul Measuring Instruments inhibiting oncogenic beta-catenin-mediated transcriptional activationThis gene encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID: 9054445).

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Description

inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin

This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria

The encoded protein may play a role in the developing kidney

PcG family members form multimeric protein complexes| which are involved in maintaining the transcriptional repressive state of genes over successive cell generations

Paxillin(Phospho Tyr118) Polyclonal Antibody, 20ul Measuring Instruments inhibiting oncogenic beta-catenin-mediated transcriptional activationThis gene encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID: 9054445).

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