Ref-1 Polyclonal Antibody, 100ul[BT-AP07734] Modified Oligos Alternative splicing results in multiple

Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing

calcium and phospholipid

this gene has increased expression

Mutations in this gene contribute to mitochondrial complex 1 deficiency

Ref-1 Polyclonal Antibody, 100ul[BT-AP07734] Modified Oligos Alternative splicing results in multipleApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.