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Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy It is a C-type lectin

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Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy It is a C-type lectinThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB) bladder cancer and osteogenic sarcoma.

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Description

It is a C-type lectin with mannose binding specificity

Widely expressed in fetal tissues

and possesses ubiquitin ligase E3 activity

It contains extracellular kringle

Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy It is a C-type lectinThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB) bladder cancer and osteogenic sarcoma.

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