FoxO1(Phospho Ser256) Polyclonal Antibody, 20ul Sealing Film Two alternatively spliced transcript variants

Two alternatively spliced transcript variants encoding different isoforms have been found for this gene

A mutation in the mouse ortholog of this gene results in homeotic| posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants

Forms heterodimers with TCF3

Interacts with SUV420H1 and SUV420H2 (By similarity)

FoxO1(Phospho Ser256) Polyclonal Antibody, 20ul Sealing Film Two alternatively spliced transcript variantsThis gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.