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MEK Kinase-1 Polyclonal Antibody, 100ul[BT-AP05333] Isothermal Amplification Mutations in this gene cause

SKU: 36898651624

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MEK Kinase-1 Polyclonal Antibody, 100ul[BT-AP05333] Isothermal Amplification Mutations in this gene causeThe protein encoded by MAP3K1 (mitogen activated protein kinase kinase kinase 1) is a serine threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF kappa B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N

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Description

Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2

and is also associated with other pathological disorders

This protein may play a role in cell death

Also found in the spleen and testis

MEK Kinase-1 Polyclonal Antibody, 100ul[BT-AP05333] Isothermal Amplification Mutations in this gene causeThe protein encoded by MAP3K1 (mitogen activated protein kinase kinase kinase 1) is a serine threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF kappa B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N

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