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NR1H2 Polyclonal Antibody, 50ul Cryopreservation Mammalian mitochondrial complex I is

SKU: 37055914249

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NR1H2 Polyclonal Antibody, 50ul Cryopreservation Mammalian mitochondrial complex I isThe liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand activated LXRs form obligate heterodimers

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Description

Mammalian mitochondrial complex I is composed of at least 43 different subunits

It locates at the mitochondrial inner membrane

Through obligatory heteromerization

resulting in the production of a fusion protein

NR1H2 Polyclonal Antibody, 50ul Cryopreservation Mammalian mitochondrial complex I isThe liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand activated LXRs form obligate heterodimers

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