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PASK Polyclonal Antibody, 20ul Peptide Modification Down-regulates expression of HIF1A and

SKU: 37113882297

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DKK97.20 DKK134.20

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PASK Polyclonal Antibody, 20ul Peptide Modification Down-regulates expression of HIF1A andThis gene encodes a member of the serine threonine kinase family that contains two PAS domains. Expression of this gene is regulated by glucose, and the encoded protein plays a role in the regulation of insulin gene expression. Downregulation of this gene may play a role in type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Description

Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes

The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein| and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway

Efficiently grow and maintain cell cultures with our Cell Culture Flask

Multiple transcript variants encoding different isoforms have been found for BCLAF1

PASK Polyclonal Antibody, 20ul Peptide Modification Down-regulates expression of HIF1A andThis gene encodes a member of the serine threonine kinase family that contains two PAS domains. Expression of this gene is regulated by glucose, and the encoded protein plays a role in the regulation of insulin gene expression. Downregulation of this gene may play a role in type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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