Tensin-1 Polyclonal Antibody, 50ul Peptide Modification Overexpression of this gene has

Overexpression of this gene has been observed in some cancer cells

This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors

a complex involved in DNA double-strand breaks by homologous recombination

Interacts with the catalytic domain of HDAC9

Tensin-1 Polyclonal Antibody, 50ul Peptide Modification Overexpression of this gene hasThe protein encoded by TNS1 (tensin 1)localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms.