CTIP(Phospho Ser327) Rabbit Polyclonal Antibody, 50ul Metabolic enzymes Component of the SCF(FBXW2) complex

Component of the SCF(FBXW2) complex containing FBXw2

This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization

This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck

Mutations in this gene result in autosomal dominant Char syndrome

CTIP(Phospho Ser327) Rabbit Polyclonal Antibody, 50ul Metabolic enzymes Component of the SCF(FBXW2) complexThe protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein which regulates cell proliferation. This protein complexes with transcriptional co repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation DNA repair and or cell cycle checkpoint control. It is suggested that this gene may