BMP-10 Polyclonal Antibody, 20ul Vessels Defects in PPT1 are a

Defects in PPT1 are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1

and the product has been shown to function interchangeably with the TAF1 product

it acts as a co-activator for several transcription factors

Several pseudogenes of this gene are found on chromosome 19

BMP-10 Polyclonal Antibody, 20ul Vessels Defects in PPT1 are aThis gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor like kinase 1 (ALK1) and plays important roles in