ATG9B Polyclonal Antibody, 20ul Centrifuges Nup93 interacts directly with the

Nup93 interacts directly with the Nup62 complex located at the center of the NPC and thus tethers the two subcomplexes

Defects in EDA are a cause of ectodermal dysplasia

This protein localizes to the nucleus and the cytoplasm

The encoded protein consists of an extracellular domain containing 7 cadherin repeats| a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins

ATG9B Polyclonal Antibody, 20ul Centrifuges Nup93 interacts directly with theThis gene functions in the regulation of autophagy, a lysosomal degradation pathway. This gene also functions as an antisense transcript in the posttranscriptional regulation of the endothelial nitric oxide synthase 3 gene, which has 3' overlap with this gene on the opposite strand. Mutations in this gene and disruption of the autophagy process have been associated with multiple cancers. Alternative splicing results in multiple transcript variants.