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GFAP Monoclonal Antibody(5C8), 50ul Cell Senescence Beta-type isoforms differ from alpha-type

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GFAP Monoclonal Antibody(5C8), 50ul Cell Senescence Beta-type isoforms differ from alpha-typeThis gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Description

Beta-type isoforms differ from alpha-type isoforms in their N-terminus

The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease| Yme1p

This gene encodes a protein which acts as a receptor for adiponectin

Required for stabilization of KCNH1 channels at the cell membrane (PubMed: 23144454)

GFAP Monoclonal Antibody(5C8), 50ul Cell Senescence Beta-type isoforms differ from alpha-typeThis gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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