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ER Alpha Monoclonal Antibody, 50ul[BT-MCA0516] Enzymes which accumulate in the brains

SKU: 38835646907

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ER Alpha Monoclonal Antibody, 50ul[BT-MCA0516] Enzymes which accumulate in the brainsThis gene encodes an estrogen receptor, a ligand activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen

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Description

which accumulate in the brains of human Alzheimer's disease patients

cerebellar Purkinje cells

It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients

Diseases associated with RPA2 include xeroderma pigmentosum

ER Alpha Monoclonal Antibody, 50ul[BT-MCA0516] Enzymes which accumulate in the brainsThis gene encodes an estrogen receptor, a ligand activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen

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