CD2AP Polyclonal Antibody, 100ul Buffers & Solutions Mutations in AKT1 have been

Mutations in AKT1 have been associated with the Proteus syndrome

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CD2AP Polyclonal Antibody, 100ul Buffers & Solutions Mutations in AKT1 have beenThis gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane