PA26 Polyclonal Antibody, 100ul Serological Pipets Alternative splicing results in multiple
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PA26 Polyclonal Antibody, 100ul Serological Pipets Alternative splicing results in multipleSESN1 encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The sestrin 1 mediates p53 inhibition of cell growth by activating AMP activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized
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