MDMX Polyclonal Antibody, 20ul Sample Library Tubes The protein encoded by ATR

The protein encoded by ATR (ATR serine/threonine kinase) belongs the PI3/PI4-kinase family

This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites

Its non-treated surface

This is the first enzyme in the biosynthesis of phosphatidylcholine/phosphatidylethanolamine in all animal cells

MDMX Polyclonal Antibody, 20ul Sample Library Tubes The protein encoded by ATRMDM4 encodes a nuclear protein that contains a p53 binding domain at the N terminus and a RING finger domain at the C terminus, and shows structural similarity to p53 binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation domain.